Longevity
14 published records
5-Amino-1MQ
5-Amino-1MQ is a small molecule NNMT (nicotinamide N-methyltransferase) inhibitor that enhances cellular NAD+ levels and mitochondrial function. Not a true peptide, but a small molecule compound…
Cardiogen (AEDR)
Cardiogen is a Khavinson bioregulator peptide consisting of four amino acids, derived from heart tissue research. Unlike larger peptides that work on cell surfaces, Cardiogen penetrates…
Epitalon (Epithalon)
Epitalon is a synthetic tetrapeptide developed by Russian scientist Vladimir Khavinson with 35+ years of research. It activates telomerase at extremely low concentrations to maintain telomere…
FOXO4-DRI (FOXO4-D-Retro-Inverso)
FOXO4-DRI is a senolytic peptide designed to selectively eliminate senescent 'zombie' cells that accumulate with age and contribute to tissue dysfunction. It works by disrupting the…
Glutathione (GSH)
Glutathione is the body's master antioxidant, a tripeptide produced naturally by the liver. It protects cells against free radicals, peroxides, and heavy metals while eliminating toxins…
Humanin (HN)
Humanin was the first mitochondria-derived peptide (MDP) discovered, originally cloned from the occipital lobe of an Alzheimer's patient. It is a 24-amino acid peptide encoded from…
Livagen (KEDA)
Livagen is a Khavinson bioregulator tetrapeptide (KEDA) with significant hepatoprotective and immunomodulatory properties. Structurally similar to Epitalon, it normalizes immune and antioxidant status while restoring liver…
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c)
MOTS-c is a mitochondrial-derived peptide that operates as a mitohormone through the Folate-AICAR-AMPK pathway. Under metabolic stress, it translocates to the nucleus to bind stress-response transcription…
NAD+ (Nicotinamide Adenine Dinucleotide)
NAD+ is a crucial coenzyme found in every cell, involved in energy generation and cellular maintenance that naturally declines with age. Supplementation may support cellular health,…
Ovagen (EDL)
Ovagen is a Khavinson bioregulator tripeptide (EDL) with primary effects on the liver and gastrointestinal tract. Developed by Dr. Vladimir Khavinson at the St. Petersburg Institute…
Pancragen (KEDW)
Pancragen is a Khavinson bioregulator tetrapeptide (KEDW) originally isolated from bovine pancreatic cells. Developed at Russia's St. Petersburg Institute of Bioregulation and Gerontology, it directly interacts…
PNC-27 (PNC27)
PNC-27 is an experimental anti-cancer peptide created by a supercomputer at SUNY Downstate Medical Center in 2000. It contains an HDM-2 binding domain from p53 (residues…
SS-31 (Elamipretide)
SS-31 (Elamipretide) is an aromatic-cationic tetrapeptide that selectively binds to cardiolipin in the inner mitochondrial membrane, preventing lipid peroxidation and optimizing electron transport chain function for…
Vesugen (KED)
Vesugen is a Khavinson bioregulator tripeptide developed at Russia's St. Petersburg Institute of Bioregulation and Gerontology. Composed of three amino acids (lysine, glutamic acid, aspartic acid),…